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INFOGEST 2.0: a standardized scientific protocol for mimicking food digestion

On April 2 was held in Granada the 6th International Conference on Food Digestion. The INFOGEST network led by Didier Dupont, INRA researcher at UMR STLO, organizes this congress. On this occasion, the new version of the in vitro digestion model INFOGEST 2.0 which has just been published in the prestigious journal Nature Protocols was presented.

système digestif. © Fotolia_12581987, fotolia.com
By Service communication Inra Bretagne-Normandie
Updated on 06/03/2019
Published on 04/01/2019

The INFOGEST international network brings together more than 400 researchers from 44 countries with the aim of improving the health properties of foods by sharing knowledge on digestion processes.

A widely shared standardized protocol

To mimic in vitro the process of digestion of food, researchers have developed many models over the years. More than 130 research protocols have been set up making it impossible to compare the results obtained by the international teams.

In 2014, the INFOGEST network developed the first harmonized in vitro static digestion model. Since its publication, this method has been the subject of more than 750 citations in the Web of Science and has been widely used around the world. The new version of the model clarifies a number of aspects of the original protocol. INFOGEST 2.0 has just been the subject of an article published in Nature Protocols under the coordination of André Brodkorb, researcher at Teagasc, with the contribution of many INRA researchers. This method thus becomes the academic and industrial standard for simulating the digestion of food. It has been validated in several in vivo trials and realistically mimics gastrointestinal digestion of dairy products. Designed for use with standard laboratory equipment, it is inexpensive and simple to encourage a wide range of researchers to adopt it.

> To find out more: link to the pdf of the article : https://doi.org/10.1038/s41596-018-0119-1

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6e conférence international sur la digestion des aliments